Sample QC - all-proteome

This document describes the results of the sample QC module.

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Tumor purity

Estimation of STromal amd Immune cells in MAlignant Tumor tissues ussing Expression data (ESTIMATE) is a computational tool to predict presence of infiltrating stromal/immune cells in tumor tissues using expression data. The tool is based on single sample Gene Set Enrichment Analysis (ssGSEA) and scores gene set signatures of stroma, immune cells and tumor purity. More information about the tool can be found here.

The box-whisker plots depict distributions of ESTIMATE scores in the different omic expression data.

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Sample correlations between omes

The heatmap below depicts correlations (Pearson’s r) calculated for each pair of ome data available for each sample. The main purpose for this analysis is to identify potential sample mix-ups during sample preparation.

RNA-PROT correlation

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CNA-RNA correlation

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CNA-PROT correlation

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Created on 2020-11-12 20:40:18

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